Anita Klopfenstein is the chief information officer of Little Caesars, where she is responsible for the overall strategic direction, development, deployment, and maintenance of technology across the organization.

Prior to Little Caesars, Klopfenstein was vice president, eCommerce and consumer systems at Panera Bread, where she oversaw consumer systems product development and commerce and marketing systems integration. With more than 25 years of successful experience managing profitable information technology departments in highly competitive markets, Klopfenstein is known for her track record of developing software products and leadership in internet, enterprise and manufacturing operations. She holds a B.S. in computer science and radio, TV, and film from Indiana State University and an M.B.A. from Liberty University. In 2017, Klopfenstein was recognized as Top Innovator at the Women in Foodservice Technology Awards. In 2021, she was recognized as the Michigan Global CIO of the Year by Inspire CIO.  In 2022 she was named CIO of they year by Inspire CIO in the Enterprise Category.

Outside of work, Klopfenstein and her husband Lynn live with their 12 children. For more than 30 years, the couple has provided foster care, and they have been named foster parents of the year several times in Illinois. Klopfenstein plays the clarinet, enjoys martial arts, and has run more than 30 marathons.