In today’s business environment, CIOs and business leaders are challenged to move their enterprises to the next level through digital business transformation, thereby providing the agility required to succeed in dynamic global markets. New technologies such as cloud, mobile, and business analytics, coupled with the right kind of organizational innovation, can create new business models and drive business opportunities. To succeed, enterprises need to assess their current stage of maturity in digital transformation to identify areas and capabilities that require strengthening. In addition, they should evaluate internal capabilities and maximize existing and potential third-party relationships. This Technology Spotlight examines these important trends and discusses the role that Hewlett Packard Enterprise (HPE) can play in helping companies achieve these goals.